Vol. 122, No. 1 (Supplement) 2017
Supplement abstract

Aerobic Training Improves Angiogenic Potential Independently of VEGF Modifications in Postmenopausal Woman

Published 2017-10-06

How to Cite

Di Baldassarre, A., Izzicupo, P., Ghinassi, B., D’Amico, M., & Nakamura, F. (2017). Aerobic Training Improves Angiogenic Potential Independently of VEGF Modifications in Postmenopausal Woman. Italian Journal of Anatomy and Embryology, 122(1), 76. Retrieved from https://oajournals.fupress.net/index.php/ijae/article/view/1844

Abstract

Purpose: To evaluate the effect of walking-training on serum angiogenic potential in postmenopausal women. Materials and Methods: Thirty-four postmenopausal women (56.18 ± 4.24 yr) participated in a 13 weeks program of walking-training. Anthropometric measures, VEGF, IL-1α, IL-1ß, IL-2, IL-8, IL-10, IL-12p70, TNF-α, C-reactive protein, insulin, IGF-1, cortisol, DHEA-S, leptin, visfatin, resistin and adiponectin were evaluated before and after training. Moreover, serum samples were tested for their ability to chemo – attract endothelial cells and to support the in vitro formation of capillary – like structures. Results: After training, the levels of IL-8, TNF-α, leptin and resistin were significantly lower, levels of DHEA-S and adiponectin increased, serum angiogenic properties improved, whereas no changes in anthropometric parameters or VEGF were detected. Conclusions: Walking training reduces inflammatory status and leads to a significant improvement in serum angiogenic properties in the absence of modifications in body composition and VEGF level.