Vol. 122, No. 1 (Supplement) 2017
Supplement abstract

The myotendinous junction plasticity following aerobic exercise

Published 2017-10-06


  • Myotendinous junction,
  • exercise,
  • muscle,
  • tendon,
  • morphology

How to Cite

Curzi, D., Salucci, S., & Gobbi, P. (2017). The myotendinous junction plasticity following aerobic exercise. Italian Journal of Anatomy and Embryology, 122(1), 68. Retrieved from https://oajournals.fupress.net/index.php/ijae/article/view/1827


The myotendinous junction (MTJ) is the site where muscle contractile force is transmitted from the myofibrils across the plasma membrane to the tendon extracellular matrix (ECM), therefore it is a key structure for the locomotor system [1]. In this work, we investigated the relationship between ultrastructural adaptations and the MTJ protein complex modulation after aerobic exercise. In particular, the answer of this anatomical interface to a month of moderate aerobic exercise has been analysed in Sprague-Dawley rats by means of confocal and transmission electron microscopy. Morphological observations confirm the exercise ability to increase the contact area between tissues, increasing the complexity of tendon finger-like processes, which penetrate into the muscle mass. Moreover, these observations suggest a possible MTJ protein complex adaptation after exercise. Confocal images, associated to an immunofluorescence quantification, confirm these ultrastructural observations. Taking together these data reveal that MTJ is a plastic interface. This plasticity can be induced by exercise, which is able to increase the contact area between tissues and to induce a protein synthesis at MTJ level.