Vol 116, No 1 (Supplement) 2011
Supplement abstract

Stemness ability of human dental pulp stem cells related to the in vivo and in vitro aging

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  • Giovanni Abatangelo,
  • Letizia Ferroni,
  • Eriberto Bressan,
  • Chiara Gardin,
  • Paolo Pinton,
  • Roberta Cortivo,
  • Stefani Sivolella,
  • Barbara Zavan

Published 2011-11-23

Keywords

  • cellule staminali adulte,
  • invecchiamento,
  • medicina rigenerativa

How to Cite

Abatangelo, G., Ferroni, L., Bressan, E., Gardin, C., Pinton, P., Cortivo, R., Sivolella, S., & Zavan, B. (2011). Stemness ability of human dental pulp stem cells related to the in vivo and in vitro aging. Italian Journal of Anatomy and Embryology, 116(2), 8. Retrieved from https://oajournals.fupress.net/index.php/ijae/article/view/4581
Copyright Notice

Abstract

“Mirror, mirror on the wall, who’s the fairest of them all?“ This is certainly the most cited expression of the 21 century. We do not want to get old, and in this context a lot of hopeful are set on stem cell therapy for tissue regeneration: regeneration of skin, dermis, cartilage, bone, nervous sistem and so on. Most of all on our smile that it is our business card. Rapid and good regeneration of alveolar bone to support new dental implant is up to now ensured by the use adult mesenchymal stem cells. But are they able to conserve their stemness ability for all the age of the donors? In light of such consideration aim of the present work has been the study of the biological properties such as proliferation and stemness ability of human adult dental pulp stem cells (DPSC) in relation to the age of the donors and to the in vitro aging. Human dental pulps derived from adult subjects aged 16–over 66 years have been isolated and cultured in presence of differentiative medium. Results obtained confirmed a correlation between age and conservation of stemness during in vitro aging.
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