Vol 118, No 1 (Supplement) 2013
Original Article

In vitro model based on human keratinocyte to evaluate relaxin activity on wound healing exploiting time-lapse video microscopy

PDF
  • Antonietta Stellavato,
  • Donatella Cimini,
  • Rosario Finamore,
  • Katia Della Corte,
  • Gilda Fiandra,
  • Mario De Rosa,
  • Chiara Schiraldi

Published 2014-01-11

Keywords

  • relaxin,
  • wound healing

How to Cite

Stellavato, A., Cimini, D., Finamore, R., Della Corte, K., Fiandra, G., De Rosa, M., & Schiraldi, C. (2014). In vitro model based on human keratinocyte to evaluate relaxin activity on wound healing exploiting time-lapse video microscopy. Italian Journal of Anatomy and Embryology, 118(1), 71–73. Retrieved from https://oajournals.fupress.net/index.php/ijae/article/view/3271
Copyright Notice

Abstract

Wound repair is a well-ordered but complex process involving many cellular activities including inflammation, growth factor and cytokine production, and thus cell migration and proliferation. In vitro wound healing assays have been used and are well accepted, for the discovery and validation of biomolecules that may influence cell migration and improve repair (Liu et al. 2009). The aim of our research was to exploit time-lapse video-microscopy (Okolab, Italy) to observe and analyse scratched monolayers of keratinocyte cell line (HaCat), with specific interest in characterizing different relaxin preparations.

PDF