Vol 118, No 1 (Supplement) 2013
Original Article

Muscular effects of relaxin on the mouse colon: mechanical and electrophysiological studies

Published 2014-01-11

Keywords

  • relaxin,
  • colon

How to Cite

Squecco, R., Garella, R., Francini, F., & Baccari, M. C. (2014). Muscular effects of relaxin on the mouse colon: mechanical and electrophysiological studies. Italian Journal of Anatomy and Embryology, 118(1), 82–83. Retrieved from https://oajournals.fupress.net/index.php/ijae/article/view/3285

Abstract

Relaxin has been reported to influence gastrointestinal motility in mice. However, at present, nothing is known about the effects of relaxin on the electrophysiological properties of the gastrointestinal smooth muscle. In the present experiments relaxin, other than influencing the colonic motility pattern, has been shown to act on cell membrane properties. The results of the present study indicate that relaxin directly modulates the motility of the proximal colon and the membrane potential of smooth muscle.